Celecoxib相关论文
目的 探讨塞来昔布联合IMRT对老年中晚期非小细胞肺癌患者有效率及肿瘤标志物的影响效果?方法 选取来院治疗的非小细胞肺癌患者80......
A clinical study of the combination of pregabalin and celecoxib on postoperative neuropathic pain af
Objective: This study investigates the efficacy of the association of pregabalin and celecoxib on postoperative neuropat......
pH-responsive nanoparticles based on algal polysaccharide for co-delivery of celecoxib and doxorubic
Objective Metastasis and chemotherapy resistance are the leading causes of breast cancer mortality.Celecoxib(CXB)has ant......
目的 检测局部应用Celecoxib对兔角膜热烧伤后继发新生血管中的MMP-2、MMP-9表达的影响,探讨Celecoxib抑制角膜新生血管的可能机制......
To overcome a selective cyclooxygenase-2(COX-2)inhibitor Celecoxib(CLX)s poor aqueous solubility and low oral bioavailab......
Effect of Celecoxib plus standard chemotherapy on serum levels of VEGF and COX-2 in patients with ga
Objective Elevated serum levels of vascular endothelial growth factor(VEGF)and COX-2 are associated with poor prognosis ......
Effects of Celecoxib on IL-6 and IL-8 levels in Xenografted Nude Mice with Human Triple-negative Bre
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Anti-LeYAntibody Enhances Therapeutic Efficacy of CelecoxibAgainstGastric Cancer by Downregulation o
Helicobacter pylori (H.pylori) is a major causative agent for the induction of chronic gastritis,gastric ulcer and gastr......
Cox2 inhibition ameliorates seizure susceptibility in a mouse model of autosomal dominant lateral te
Autosomal dominant lateral temporal epilepsy(ADLTE)is an inherited epilepsy syndrome caused by mutations in Lgi1 gene.It......
Celecoxib, a selective cox-2 inhibitor, has been shown to prevent the heterotopic ossification following total hip arthr......
The Inhibitory effect of celecoxib on Lewis lung carcinoma cell line by regulation of cyclooxygenase
Aim: Celecoxib is a potent nonsteroid anti-inflammatory drug (NSAID) that has demonstrated great promise in cancer chemo......
Celecoxib antagonizes the cytotoxicity of oxaliplatin in human esophageal squamous cell carcinoma ce
Our previous study demonstrated that COX-2 selective inhibitor celecoxib antagonized the cytotoxic action of cisplatin a......
Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor used for the treatment of pain and inflammation.Emerging and......
目的探讨塞来昔布(celecoxib)增强肿瘤坏死因子相关凋亡诱导配体(tumor necrosis factor-related apoptosis-inducing ligand，TRAIL......
目的 观察环氧合酶-2(COX-2)特异性抑制剂Celecoxib对胃癌SGC7901/ADR细胞多药耐药1(mdr1)基因表达、核转录因子(NF)-κB激活水平......
BACKGROUND Pelvic lipomatosis(PL)is a rare benign condition with characteristic overgrowth of histologically benign fat ......
昔布类药物(塞莱昔布Celecoxib、罗非昔布Rofecoxib)为环氧酶-2(cox-2)特异性抑制性,是结肠息肉的良好防治剂。罗非昔布化学名为:4......
如何提高肝癌的治疗效果,降低发生率及死亡鲻率,一直是医学研究的热点.近年来,非甾体类消炎药物(NSAIDs)的抗肿瘤作用已逐步得到认......
目的 评估术前和术后联合使用塞来昔布(选择性环氧合酶2抑制剂),对人工全膝关节置换术后疼痛的影响,以观察其安全性和对减少术后阿......
目的 探讨芳香化酶 (p4 5 0arom )基因、环氧合酶 2(COX 2 )基因mRNA在子宫内膜异位症 (内异症 )患者异位及在位子宫内膜组织中......
Celecoxib是一种环氧合酶2(COX-2)特异性抑制剂,临床试验证实可用以改善骨关节炎和风湿性关节炎患者的症状、体征。作者研究评估C......
Tumor-infiltrating lymphocytes (TIL) were once considered as the effector cells in the immune attack against cancer.Howe......
心脏病发作后不论服用Cox-2 抑制剂,还是服用其他的非甾体类抗炎药物(NSAIDs),都会增加死亡危险,该结论是由丹麦哥本哈根 Bispebji......
迄今关于特异性环氧合酶-2(COX-2)抑制剂与需接受治疗的血压升高危险间关系尚存在争议。本文就COX-2与新发高血压危险间关系进行评......
目的:检测环氧合酶-2(COX-2)在兔主动脉粥样硬化(AS)中的表达及其与AS病变的相关性,观察血管紧张素Ⅱ受体阻断剂厄贝沙坦(irbesart......
AIM: To investigate the effects of periocular injection of propranolol and celecoxib on ocular levels of vascular endoth......
Design,Synthesis and in vitro Evaluation of a New Class of Novel Cyclooxygenase-2 Inhibitors:3,4-dia
design, synthesis and in vivo evaluation of a new class of COX-2 inhibitors 3, 4-diaryl-3-pyrrolin-2-ones are reported.
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Bile from a patient with anomalous pancreaticobiliary ductal union promotes the proliferation of hum
AIM:To explore the effects of COX-2 gene in theproliferative activity induced by bile from anomalouspancreaticobiliary ......
Celecoxib inhibits proliferation and induces apoptosis via prostaglandin E_2 pathway in human cholan
AIM:To evaluate the roles and mechanisms of celecoxib ininducing proliferation inhibition and apoptosis of humancholang......
Anti-cancer effects of COX-2 inhibitors and their correlation wit angiogenesis and invasion in gastr
AIM:To observe the anti-cancer effects of COX-2 inhibitorsand investigate the relationship between COX-2 inhibitorsand ......
AIM: To investigate effects of cyclooxygenase 2 (COX-2) inhibitors on nasopharyngeal carcinoma (NPC) cells and on angio......
本实验应用四唑氮蓝(MTT)比色法检测先天性胆总管囊肿(CCC)胆汁对体外培养人胆管癌细胞增生的影响,旨在观察胆汁在CCC癌变中的作用......
近年文献报道,经十二指肠Oddi括约肌成形术(transduodenalsphincteroplasty ,TS)患者远期胆管癌发生率比正常人群明显增高[1] ,但......
环氧化酶-2(Cyclooxygenase-2,COX-2)是诱导型前列腺素内过氧化物合成酶.研究显示COX-2过度表达与某些上皮性肿瘤的发生发展关系密......
一、COX 2与COX 1 :两种同功酶的必要性由膜磷脂质以磷脂酶切断的游离花生四烯酸 (AA)通过COX途径可生成前列腺素 (PG)E2 、PGF2α......
Phase Ⅰ/Ⅱ study of selective cyclooxygenase-2 inhibitor celecoxib as a radiation sensitizer in patie
Purpose:The primary goal of this phase I/II study was to evaluate the feasibility, safety and efficacy of celecoxib admi......
目的 Stat3(signal transduction and activators of transcription-3),是重要的信号转导与转录因子,与细胞的异常增殖密切有......
目的探讨脑胶质瘤微环境及环氧化酶2抑制剂塞来昔布对树突状细胞(dendritic cell，DC)表型和功能的影响。方法检测塞来昔布对C6细胞C......
Combination of fasudil and celecoxib promotes the recovery of injured spinal cord in rats better tha
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目的 探索塞来昔布对细粒棘球蚴原头节体外生长及p-ERK2表达的影响.方法 实验分组为1640培养基组、DMSO组、塞来昔布溶液(50、100......
目的探讨透明质酸钠联合塞来昔布治疗老年人膝骨关节炎的治疗效果及应用价值。方法将120例老年膝骨关节炎患者采用随机数字表法分......
目的探讨塞来昔布用于食管癌患者放化疗过程中增敏效果及临床应用价值。方法采用随机数字表法将60例食管癌患者分为观察组和对照组......
目的：观察Neurotropin联合Celecoxib治疗膝关节骨性关节炎(kneeosteoarthritis，KOA)的疗效和安全性。方法采用随机、平行对照研究临......
目的研究选择性环氧合酶-2抑制剂——塞来昔布对大鼠颅脑创伤后凋亡蛋白Bcl-2和Bax表达的影响。方法按照体重将SD大鼠随机分为4组:......
